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How To Reduce Sperm Liquefaction Time

Male Infertility

Infertility is caused by a male person gene in approximately 30%-forty% of cases. An additional 20% of infertile couples are institute to have both male and female factors.

What Causes Male Infertility?

Most cases of male infertility (xc%) can be attributed to sperm product

CAUSES OF MALE INFERTILITY

  • Sperm production abnormalities
  • Sperm transport disorders
  • Erectile dysfunction
  • Ejaculation disorders

Abnormalities resulting in low sperm count and/or poor motility (i.e. the number of sperm which are viable and moving). Abnormal morphology (i.e. malformed sperm) appears to play a bottom function in male person infertility. While at that place are many theories about what causes these conditions, information technology is not e'er possible for the fertility specialist to place the cause. Sometimes an infection may be discerned past finding inflammatory or white cells in the semen. A semen culture can identify the organism involved and antibiotics can be prescribed to resolve the problem. Sometimes the cause of sperm abnormality can be traced to genetic abnormalities, past testicular infection, ecology causes (such equally smoking, hot tubs and marijuana utilise), hormonal deficiency (Hypogonadism), or genetic defects (cystic fibrosis). Information technology is becoming more mutual to meet men with low sperm count every bit a consequence of steroids or testosterone shots given to them at the local gym to help them bulk up. The presence of a varicocele or distended testicular veins may event in temperature elevation in the testes resulting in aberrant sperm production.

  • The remaining cases of male infertility (10%) may exist attributed to obstructions in sperm transport caused by infection or congenital absence of the vas or epididymis. Sometimes, stress, depression, alcohol, certain medications and low testosterone level may crusade temporary erectile problems which may affect the couple's power to have sexual intercourse. At other times, the trouble may be attributed to retrograde ejaculation or ejaculation into the bladder. This tin can happen after bladder or intestinal surgery, with certain medications or stricture (narrowing) of the urethra.
  • Aging causes a decline in the count, move and genetic quality of the sperm.
  • Different female infertility, which requires a battery of tests to diagnose, male infertility is a relatively uncomplicated evaluation consisting of medical history, physical examination and a semen analysis. If it is normal, normally, no other testing of the male partner is required.
  • Of course, the couple should ensure that the laboratory performing the semen analysis is highly experienced in this procedure and that the lab performs a complete evaluation.
  • If the semen analysis shows that there is a problem, an evaluation by an urologist- ideally i who specializes in infertility is necessary. Your partner tin wait to undergo a careful exam, claret tests and an ultrasound to endeavour to pinpoint the crusade

Male Infertility – Medical History

The Male Partner – Medical History

  • Duration of infertility/sexual frequency
  • Testicular surgery or injury
  • Childhood illnesses
  • Heat exposure; pesticide exposure
  • Medications
  • Smoking, booze and drug abuse
  • Sexually transmitted diseases

Male Infertility – Concrete Test

The urologic examination may reveal abnormalities of the penis or testicles, or the presence of a varicocele (abnormal enlargement of the veins in the scrotum).

Male person Infertility Testing – The Semen Analysis

In this test, freshly ejaculated semen is examined under the microscope to evaluate the number and quality of sperm and several other characteristics of the semen.

Why the Test is done?

  • Infertility: The semen analysis is one of the outset tests done to help determine if a human being has an infertility trouble. About 15% of couples experience problems conceiving, and twoscore% of the time, the problem tin can be traced to a male person factor.
  • After vasectomy (male sterilization): The semen assay is performed about 6 weeks later surgery to brand sure that at that place is no sperm present in the ejaculate, confirming that the human is sterile.
  • After vasectomy reversal: The semen analysis is washed to decide if there is sperm present in the ejaculate, indicating that the reversal was successful and fertility has been restored.

Normal Semen Analysis Results

  • Count (the number of sperm) – sperm concentration is the number of sperm per milliliter. Boilerplate concentration is about sixty 1000000 per milliliter. A sperm concentration of over 20 1000000 per milliliter is considered normal.
  • Motility (the percentage of moving sperm) – Motility is considered normal when at least 50% of observed sperm, prove good forrard movement. These are the strongest sperm, swimming fast in a directly line (Grade four). Some of the sperm may be moving slower in a circle or in kleptomaniacal lines (Grade 3). Other sperm movement their tail but have no forward motion (Grade two) or fail to move at all (Course 1).
  • Morphology (the size and shape of the sperm) – Morphology is considered normal if 14% or more of the observed sperm have normal shape.
  • Volume – greater than 2.0 milliliters is considered normal. A low volume may reflect complete or partial blockage of gland secretions contributing to the seminal fluid. If the volume is less than 1 milliliter, the semen may not be in close enough proximity to the cervix to let sufficient sperm to swim upwards to the uterus and fallopian tube.
  • White Blood Cells – Finding bacteria or white blood cells in the semen bespeak that an infection may be present. A semen civilization may identify the organism involved and antibiotics tin be prescribed to resolve the problem. A repeat semen analysis usually follows.
  • PH level – normal pH range is 7.two – viii.0. Too little or too much acid in the semen is detrimental to the sperm.
  • Liquefaction – It usually takes less than 20 minutes for semen to change from a thick gel into a liquid. An unusually long liquefaction time may point an infection.
  • Fructose level – Semen is analyzed for fructose when at that place is no sperm in the ejaculate (azoospermia) or if the semen book is very low (less than 1 ml). Absence of fructose in the semen may point blockage of the seminal vesicles which secrete a pregnant corporeality of the fluid of the ejaculate.

What Abnormal Results Mean

  • Semen samples may vary from day to day, and so if the test is abnormal, you may be asked to repeat information technology in a month to reevaluate the abnormality. An evaluation by a urologist is necessary to pinpoint the crusade for the problem.
  • Sometimes the cause of sperm abnormalities can exist traced to genetic defects (cystic fibrosis), hormonal deficiency, environmental factors (such as smoking, hot tubs and marijuana utilise), or blockage of the ejaculatory ducts.
  • Low sperm count can occur in men who are treated with testosterone or anabolic steroids.
  • If a varicocele (distended testicular veins) is nowadays, information technology may disrupt sperm production.
  • In some men, low sperm count or complete absence of sperm (azoospermia) may be attributed to deletions of very small-scale regions in their Y chromosome (detectable by genetic studies).

Absence of sperm in the semen may exist caused past:

  • Ejaculation of the sperm into the bladder (retrograde ejaculation);
  • Congenital absenteeism of the vas deferens (sperm ship ejaculatory duct);
  • Scarring of the ejaculatory duct;
  • Testicular failure;
  • Surgery, chemotherapy or radiation treatment for cancer;

Testicular failure can be distinguished from sperm send abnormalities by measuring the married man's hormone levels; these may include Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Inhibin, Testosterone, Prolactin and Thyroid stimulating Hormone (TSH). Testicular biopsy is sometimes recommended to see if the testes are producing sperm.

Tests for Sperm Deoxyribonucleic acid Impairment

Infertile men, with abnormal sperm count are more likely to take increased sperm Deoxyribonucleic acid harm. The cause for this is not articulate but it may occur equally a issue of oestrus exposure, radiation or chemotherapy, infection, cigarette smoking and varicocele. At that place are several tests for sperm Dna damage (SDD, SCSA). Their usefulness is questionable and The Practice Committee of the American Society for Reproductive Medicine issued the following statements:

  • Existing information on the relationship between abnormal Dna integrity and reproductive outcomes are limited.
  • Sperm DNA damage is more common in infertile men and may bear on reproductive outcomes in selected couples, including those with recurrent spontaneous miscarriage or unexplained infertility
  • At nowadays, the results of sperm Deoxyribonucleic acid integrity testing alone practice not predict pregnancy rates achieved with intercourse, IUI, or IVF and ICSI.
  • Currently, at that place is no proven function for routine DNA integrity testing in the evaluation of infertility.
  • Treatments for abnormal DNA integrity have not been shown to accept clinical value.

Handling of Male Infertility

One time the cause for the infertility is identified, your doctor will recommend the appropriate therapy.

  • Antibiotic treatment Antibiotic medication is prescribed for 10-21 days if an infection is present.
  • Lifestyle changes Discontinue smoking, drinking and drug use. Anabolic steroids for body building should be avoided because of severe and potentially irreversible suppression of sperm production. Avoid exposure to heat and environmental toxins.
  • Hormonal Handling with medications such as HCG and HMG (gonadotropins) injections is recommended for men with low pituitary FSH and LH levels. Clomiphene tablets 25-50mg every other day is sometimes advised in men with low sperm count and low testosterone levels. Men with an elevated prolactin level tin be treated with a prolactin lowering medication (bromocriptine).
  • Retrograde ejaculation Ejaculation of sperm into the bladder can be treated with medications such as pseudoephedrine which helps close the bladder cervix, preventing sperm from entering the float. Another option is to recover sperm from the urine after ejaculation. In these cases, a single sperm is injected into each egg (ICSI) during In Vitro Fertilization (IVF).
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Varicocele

Abnormal dilatation of the testicular veins can be found in well-nigh 15 % of normal males and in xl% of infertile males. Well-nigh all varicoceles occur on the left side. Varicocele is thought to cause sperm abnormalities by increasing blood flow to the testicles and raising testicular temperature. Varicocele tin be reliably diagnosed past palpation of the scrotal sac and Doppler ultrasound. Whether or not varicocele causes infertility is controversial. Some urologists advocate surgery to remove the dilated veins (varicocelectomy) but the benefits of the surgery have not been conclusive. For the older couple with diminishing ovarian reserve, IVF and ICSI should be offered without filibuster. A not surgical alternative to varicocelectomy is a radiological treatment called Embolization. The process is performed by an interventional radiologist who will be inserting a thin wire into the veins, draining the testis, and injecting small particles into the veins to close them off.

Intrauterine Insemination (IUI)

UI is indicated for mild to moderate sperm abnormalities. The husband's semen is washed with special culture media to remove dead sperm, inflammatory cells and bacteria and is then injected into the uterus utilizing a soft catheter. The procedure is most constructive when combined with ovulation induction therapy for the wife. The wife is given gonadotropin hormone injections for about 10 days to stimulate the development of two-4 eggs, improving the likelihood of fertilization afterward IUI. In Vitro Fertilization is often recommended after 3-vi unsuccessful IUI treatment cycles or in older female person partners who demand to consider IVF sooner because of the business organisation well-nigh deterioration in the quality of their eggs.

In Vitro Fertilization (IVF)

IVF is ofttimes recommended for astringent sperm abnormalities and failed IUI. IVF is a process of fertilizing an egg with a sperm in the laboratory (in vitro) to produce an embryo. The embryos are then transferred into the uterus to initiate a pregnancy.

ICSI (Intracytoplasmic Sperm Injection)

ICSI is a laboratory technique for injecting a unmarried sperm into an egg using a high power manipulating microscope.

A single sperm is loaded into a thin glass needle, the needle is then advanced through the egg beat out or zona pellucida and into the egg's cytoplasm. The sperm is then injected into the egg and the procedure is repeated until all of the eggs are injected. The eggs are returned to the incubator and checked the following day to see how many fertilized. Well-nigh 80% of the injected eggs will fertilize normally to produce a zygote.

Testicular Sperm Extraction (TESE)

  • When sperm is present in the testes, but not in the ejaculate, it tin can exist retrieved from the testicle by direct biopsy (TESE) or by fine needle biopsy technique chosen Testicular Sperm Aspiration (TESA). The extracted testicular sperm can be utilized in an In Vitro Fertilization (IVF) process where a single sperm is injected into the egg (ICSI).

Donor Insemination

  • Donor sperm insemination is a relatively depression toll culling handling for couples with male person infertility who do non wish to consider In Vitro Fertilization (IVF), or in cases where despite all efforts, no sperm could exist retrieved from the male partner for IVF treatment.

Adoption

  • With proper evaluation and treatment, well-nigh infertile couples will eventually conceive. For those couples who remain infertile, adoption is oft considered. At that place are numerous adoption agencies that specialize in different types of adoptions including domestic private, domestic public and international adoptions.

IVF (In vitro Fertilization) center offering State of the Art fertility treatments since 1982

Experience

A pioneering and successful fertility centre since 1982, Boca Fertility was the kickoff IVF center in Palm Beach Canton to reach a successful pregnancy and commitment of a babe conceived through IVF. Endless numbers of infertile couples are now parents thanks to the intendance they received at Boca Fertility.

Success

Our IVF program consistently achieves loftier success rates (SART Dispensary Summary Report - Sartcorsonline.com), utilizing state of the art techniques such as IntraCytoplasmic Sperm Injection (ICSI), Testicular Sperm Extraction (TESE), Preimplantation Genetic Diagnosis (PGD), egg and embryo freezing, gestational surrogacy and donor egg IVF.

Personalized Care

Boca Fertility is physician-owned, so you tin look to receive unparalleled individualized and empathetic intendance. Yous will exist cared for by only one doctor, and you lot volition discover our staff to be truly supportive. Yous will be pleased by the relaxed atmosphere and the very personal attention y'all receive at Boca Fertility.

Source: https://bocafertility.com/male_infertility/

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